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Exstream Command centre JMS Real-time App not working

We have been upgrading to Command centre 3.1.1 and in process of configuring Command centre Real-time(CC RT) Engines using JMS Queue. CC RT is getting halt as we start them with below Error:

Exception in thread "main" java.io.IOException: JNDI setup failed on RNAME=nsp://ist-pppesb-t2.axa-uk-test.intraxa:8000
at com.exstream.connector.JMSConnector.open(JMSConnector.java:125)
at com.hp.exstream.project.axa.healthcare.ddaoutput.DDAOutputMerge.open(DDAOutputMerge.java:88)
Caused by: javax.naming.CommunicationException: JNDI setup failed on RNAME=xxxx.yyyy.zzz(Webmthods JMS provider URL[)
Root exception is com.pcbsys.nirvana.client.nRealmUnreachableException: Realm is currently not reachable:com.pcbsys.foundation.base.fException: Retry count=2 exceeded attempting to connect to host - [nsp://ist-pppesb-t2.axa-uk-test.intraxa:8000/]]
at com.pcbsys.nirvana.nSpace.NirvanaContext.(NirvanaContext.java:144)
at com.pcbsys.nirvana.nSpace.NirvanaContext.(NirvanaContext.java:74)

I could see below error in CC Server log:

ERROR org.springframework.jms.listener.DefaultMessageListenerContainer:requestQueueContainer-1 - Could not refresh JMS Connection
for destination 'IBQ' - retrying using FixedBackOff{interval=60000, currentAttempts=0, maxAttempts=unlimited}. Cause: Could not connect to broker URL: tcp://localhost:61616. Reason: java.net.ConnectException: Connection refused (Connection refused).

Please assist in resolving this connection issue.