OD affecting ACCESS ?

System

We suspect that recent upgrade of OPEN DEPLOY (OD 560 SP1) onto our IIS Web Server has caused our other applications that use ACCESS DB to fail with the following error.
Microsoft OLE DB Provider for ODBC Drivers (0x80004005)
[Microsoft][ODBC Microsoft Access Driver] The Microsoft Jet database engine cannot open the file '(unknown)'. It is already opened exclusively by another user, or you need permission to view its data.
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Has anybody come across this before - we will have to backout OD until a solution is found.

Thanks
Pete